Ureteric reflux and kidney scarring in children.
نویسندگان
چکیده
Vesico-ureteric reflux is commonly found in children who are investigated because of urinary tract infection. By allowing back-flow of infected urine from bladder into ureter, reflux may cause progressive damage to the upper urinary tract, such as dilatation of the ureter and scarring in the kidney. Hodson and Edwards (1960) noted that reflux was often associated with kidney scarring, and McGovern, Marshall, and Paquin (1960) made the striking statement that 'all upper urinary tracts with reflux are dying but at different rates'. Yet not everyone is convinced that the operative treatment of reflux is necessary. The occasional spontaneous disappearance of reflux when infection is controlled, and the markedly decreased incidence in adolescents and adults led Baker et al. (1966) to 'question whether the majority of children with reflux are not surgically overtreated'.
منابع مشابه
The deletion polymorphism of the ACE gene is not an independent risk factor for renal scarring in children with vesico-ureteric reflux.
BACKGROUND The deletion (D) polymorphism of the gene encoding angiotensin-I converting enzyme has been implicated as a risk factor for progressive renal disease in several conditions. This study was designed to evaluate the association between homozygosity for the D allele and susceptibility to renal scarring in children with vesico-ureteric reflux (VUR). METHODS Two-hundred-and-six children ...
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Vesicoureteral reflux (VUR) is the retrograde passage of urine from the bladder to the upper urinary tract. It is the most common congenital urological anomaly affecting 1-2% of children and 30-40% of patients with urinary tract infections. VUR is a major risk factor for pyelonephritic scarring and chronic renal failure in children. It is the result of a shortened intravesical ureter with an en...
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Much of the confusion in the discussion of these topics reflects differences of nomenclature not of fact, and a failure to relate the wide variation in severity both of reflux and of renal damage to their long-term implications. In this article, significant bacteriuria denotes the presence of actively multiplying organisms in the urinary tract and is indicated in girls by a pure growth of at le...
متن کاملBacteriuria, reflux, and renal scarring
Much of the confusion in the discussion of these topics reflects differences of nomenclature not of fact, and a failure to relate the wide variation in severity both of reflux and of renal damage to their long-term implications. In this article, significant bacteriuria denotes the presence of actively multiplying organisms in the urinary tract and is indicated in girls by a pure growth of at le...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 43 230 شماره
صفحات -
تاریخ انتشار 1968